Neurodegeneration Challenge Network

Neurodegenerative diseases, like Alzheimer’s, Parkinson’s, ALS, and Huntington’s Disease, are a leading cause of death and disability worldwide. There are no effective therapies to prevent, cure, or treat most of these disorders. To make progress, we’ve developed a new kind of collaborative network — one that brings new ideas and new people into the field, supports them with well-validated tools and resources, and asks them to look at this problem from a cross-disease perspective.

The Neuroscience program was launched in 2018 with a focus on neurodegenerative disease and centered on the CZI Neurodegeneration Challenge Network (NDCN). The Challenge Network model is built on the vision that progress in solving neurodegenerative diseases will come from bringing new talent and ideas from diverse disciplines and expertise into the neurodegeneration field, building interdisciplinary collaborations, empowering the broader scientific community with robust tools and platforms, and creating a culture of innovation, collaboration, and open science.