About CZI

The Chan Zuckerberg Initiative was founded in 2015 by Priscilla Chan and Mark Zuckerberg to help solve some of society’s toughest challenges — from curing or preventing disease to improving education and addressing the needs of our local communities. We provide the operational support across our areas of work.

Our Leadership
Inside a lab with modern instruments and monitors visible, a scientist in a blue lab coat gestures toward a large piece of equipment while Mark Zuckerberg and Priscilla Chan lean in to observe closely.
Photo by Cody Pickens for Forbes
Photo by Cody Pickens for Forbes

Our Focus Areas

Science

We’re leading the new era of AI-powered biology. At the Biohub, we bring together scientists, engineers, and AI experts with a shared mission to help scientists cure or prevent all disease.

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Education

Our mission is to bring learning science into the tools used every day by teachers and students, ensuring that technology reflects the realities of classrooms and strengthens teaching and learning.

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Supporting Our Work

Three people talking and sharing a meal at a large table during a Ventures event.

Grants & Ventures

Through grantmaking and our venture portfolio, we invest in bold ideas that have the potential to accelerate change. Since 2015, CZI has awarded approximately $7.22 billion in grants and invested nearly $300 million in ventures whose work aligns with our values.

Local Giving

A group of people stand in front of a colorful mural in the CZI Community Space, smiling and raising their hands in a celebratory pose.

Supporting Our Communities

Mark and Priscilla support the communities where they live and work by partnering with local nonprofits, supporting local solutions, and addressing emerging needs to help these communities thrive.

CZI carries out its work through the Chan Zuckerberg Initiative, LLC; the Chan Zuckerberg Initiative Foundation (a 501(c)(3) private foundation); the Chan Zuckerberg Initiative Donor-Advised Fund (DAF) at the Silicon Valley Community Foundation; and Chan Zuckerberg Initiative Advocacy, (a 501(c)(4) organization).